Why Strength Training After 45 Is the Single Best Investment in Your Long-Term Health
Two large studies found that lifting weights just a few times a week is linked to double-digit reductions in your risk of dying from heart disease, cancer, and diabetes combined.
- Muscle mass and strength begin declining years before most people notice, which means the "best time to start" strength training was probably a while ago — the second-best time is now.
- A 2022 meta-analysis found resistance training was associated with a 15% lower risk of all-cause mortality, a 19% lower risk of cardiovascular mortality, and a 14% lower risk of cancer mortality compared to doing none.
- A separate 2022 meta-analysis found muscle-strengthening activity was linked to a 10-17% lower risk of all-cause mortality, cardiovascular disease, cancer, and diabetes — independent of aerobic exercise — and both studies found the mortality benefit peaked at a modest weekly volume.
- A 2025 meta-analysis of postmenopausal women found resistance training produced measurable improvements in bone mineral density at the spine, hip, and femoral neck — directly relevant to fracture risk after 45.